High Fructose Corn Syrup

Completed · Not applicable

Conditions studied: Nonalcoholic Fatty Liver Disease, Obesity

In brief

The purpose of this research study is to learn more about how high fructose corn syrup, a sugar used to sweeten drinks and foods, affects metabolism in obese persons with and without nonalcoholic fatty liver disease. Eligible participants will be studied before and after eating a diet high in high fructose corn syrup or a standard diet (low in high fructose corn syrup) for four weeks.

Key facts

Study ID

NCT02018237

Run by

Washington University School of Medicine

People needed

47

Starts

2012-03-01

Expected to finish

2016-03-01

Last updated by the study team

2017-03-27

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• IHTG >6.5% or <5%
• BMI 30.0-45.0 kg/m²
• Sedentary
• Consume <10% calories from high fructose corn syrup
• Weight stable for previous 3 months

You may not qualify if…

• IHTG 5.1-7.9%
• Children
• Adults over 65 years
• Pregnant
• Lactating
• Exercise >1.5 hours/week
• Hepatitis B or C
• Diabetes
• History of liver disease
• History of alcohol abuse
• Severe hypertriglyceridemia (>300 mg/dl)
• Smokers
• Anemia (Hemoglobin <10mg/dl)
• Not weight stable

Where it is running

• Washington University School of Medicine — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

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