Evaluation of Objective Perimetry Using Chromatic Multifocal Pupillometer

Recruiting now

Conditions studied: Retinal Dystrophies, Retinitis Pigmentosa, Glaucoma

In brief

Objective perimetry can better monitor visual field defects in retinal dystrophy and Glaucoma patients than conventional subjective perimetry. The PLR ( Pupil Light Reflex to short and long wavelength stimuli should be significantly lower compared to healthy participants in areas of visual field defects in retinal dystrophy and Glaucoma patients.

Key facts

Study ID

NCT02014389

Run by

Sheba Medical Center

People needed

200

Starts

2013-12-01

Expected to finish

2026-12-31

Last updated by the study team

2024-04-25

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 18-80 years old.
• Signing informed consent.
• Pupillary reflex to light.

You may not qualify if…

• Cloudy corneas.
• Surgical intraocular ophthalmic procedure within the past 30 days.
• No reactive pupils.
• Synechia of the iris to the lens after surgery or inflammation.
• Neovascularization.
• Axenfeld-Rieger Syndrome.
• Iris atrophy (ICE syndrome).
• Iris coloboma.
• Sphincter damage due to ischemia.
• Sphincter damage due to trauma (tears of sphincter or diffuse damage to muscle).
• Sphincter damage due to Herpes Zoster Uveitis.
• Sphincter damage due to high intraocular pressure.
• Iris tumor or cyst.
• Ectropion uvae.
• Adie's pupil.
• Third nerve aberrant regeneration of the iris sphincter.
• RP patients with Optic neuropathy with the potential of producing a positive RAPD (Relative Afferent Pupillary Defect).
• Chronic use of myotics or mydriatics.
• Systemic medication that have affect on pupillary reflex .
• Any condition preventing accurate measurement or examination of the pupil.

Where it is running

• Sheba Medical Center — Tel Litwinsky, Israel (enrolling)

Full record on ClinicalTrials.gov

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