Diurnal Variability in the Regulation of Beta-cell Function and Insulin Sensitivity in Overweight People

Completed

Conditions studied: Overweight

In brief

The purpose of this research study is to learn more about how our body produces sugar, breaks down fat for fuel, and makes insulin (the major hormone that controls the production of blood sugar and fat breakdown) during a 24-hour day and how body fat and muscle are involved in these processes.

Key facts

Study ID

NCT02011581

Run by

Washington University School of Medicine

People needed

16

Starts

2011-10-01

Expected to finish

2014-03-01

Last updated by the study team

2015-04-30

Who can join

Age: 18 and older, up to 55. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Females
• 18-55 years old
• BMI between 25.0-29.9 kg/m2
• Must be sedentary (regular exercise <1hour/week or <2 times/week

You may not qualify if…

• Regular exercise (>1hour/week or >2 times/week)
• Diabetes
• Severe organ dysfunction
• Smokers
• Severe hypertriglyceridemia (>300 mg/dl)
• Medications that may alter the results of the study
• Pregnant
• Breastfeeding

Where it is running

• Washington University School of Medicine — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

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