Study of Idalopirdine in Patients With Mild - Moderate Alzheimer's Disease Treated With an Acetylcholinesterase Inhibitor

Completed · Phase 3 · Has a placebo group

Conditions studied: Alzheimer's Disease

In brief

To establish efficacy of idalopirdine as adjunctive therapy to acetylcholinesterase inhibitors (AChEIs) for symptomatic treatment of patients with mild-moderate Alzheimer's disease (AD).

Key facts

Study ID

NCT02006654

Run by

H. Lundbeck A/S

People needed

734

Starts

2014-03-01

Expected to finish

2017-01-01

Last updated by the study team

2018-02-07

Who can join

Age: 50 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• The patient has a knowledgeable and reliable caregiver.
• The patient is an outpatient.
• The patient has probable AD.
• The patient has mild to moderate AD.
• Stable treatment with an AChEI.
• The patient, if a woman, must have had her last natural menstruation ≥24 months prior to baseline, OR be surgically sterile.
• The patient, if a man, agrees to protocol-defined use of effective contraception if his female partner is of childbearing potential, OR must have been surgically sterilised prior to the screening visit.

You may not qualify if…

• The patient has evidence of any clinically significant neurodegenerative disease, or other serious neurological disorders other than AD.
• The patient has a Diagnostic and Statistical Manual of Mental Disorders, 4th edition, Text Revision (DSM-IV-TR) Axis I disorder other than AD.
• The patient has evidence of clinically significant disease.
• The patient's current AChEI therapy is likely to be interrupted or discontinued during the study.
• The patient is currently receiving memantine or has taken memantine within 2 months prior to screening.
• Other inclusion and exclusion criteria may apply.

Where it is running

• US625 — Bellflower, California, United States
• US626 — Costa Mesa, California, United States
• US604 — Oxnard, California, United States
• US627 — Santa Ana, California, United States
• US609 — Danbury, Connecticut, United States
• US614 — Norwalk, Connecticut, United States
• US608 — Deerfield Beach, Florida, United States
• US616 — Hialeah, Florida, United States
• US620 — Miami, Florida, United States
• US603 — North Palm Beach, Florida, United States
• US631 — Port Charlotte, Florida, United States
• US622 — Elk Grove Village, Illinois, United States
• US611 — Elkhart, Indiana, United States
• US606 — Prairie Village, Kansas, United States
• US601 — Farmington Hills, Michigan, United States
• US607 — St Louis, Missouri, United States
• US613 — Lawrenceville, New Jersey, United States
• US635 — Paterson, New Jersey, United States
• US630 — Toms River, New Jersey, United States
• US621 — Albany, New York, United States
• US632 — Staten Island, New York, United States
• US633 — Charlotte, North Carolina, United States
• US623 — Oklahoma City, Oklahoma, United States
• US618 — Norristown, Pennsylvania, United States
• US612 — Mesa, Arizona, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.