Imaging Kidney Transplant Rejection Using Ferumoxytol-Enhanced Magnetic Resonance

Completed · Not applicable

Conditions studied: Renal Transplant Rejection

In brief

The goal of this study is to develop a non-invasive imaging test for in vivo detection of kidney transplant rejection. The hypotheses are that 1) Ferumoxytol-MRI can generate accurate estimates of tissue iron concentrations and tissue macrophages. 2) The signal given by a renal allograft on Ferumoxytol-MRI demonstrates significant differences between rejected and non-rejected transplants.

Key facts

Study ID

NCT02006108

Run by

Stanford University

People needed

21

Starts

2012-11-27

Expected to finish

2017-04-11

Last updated by the study team

2018-05-11

Who can join

Age: 8 and older, up to 40. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Completed solid organ transplant with referral for transplant follow-up

You may not qualify if…

• Exclusion criteria comprise MR-incompatible metal implants, need of sedation (since an anesthesia is not supported by this), claustrophobia or hemosiderosis/hemochromatosis.

Where it is running

• Lucile Packard Children's Hospital — Stanford, California, United States

Full record on ClinicalTrials.gov

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