Effect of Exercise on Metabolic Health

Completed · Not applicable

Conditions studied: Obesity

In brief

One of the main objectives of this study will be to assess potential differences in important risk factors associated with Metabolic Syndrome in overweight adults who do not participate in a regular exercise program compared with overweight individuals who do exercise regularly. In addition, we will determine the effects of a single, modest session of exercise on the body's ability to control blood sugar and regulate fat metabolism in obese sedentary adults vs. obese adults who live a physically active lifestyle. Our study focuses on identifying mechanisms responsible for improved insulin action related to regular exercise and to provide novel targets for preventing and treating type 2 diabetes.

Key facts

Study ID

NCT02001142

Run by

University of Michigan

People needed

15

Starts

2013-11-01

Expected to finish

2016-09-17

Last updated by the study team

2022-03-21

Who can join

Age: 18 and older, up to 40. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Body Mass Index [BMI] = 30-45 kg/m2, fasting blood glucose concentration must be < or = to125 mg/dl, Hematocrit > or = to 34%, all women must be pre-menopausal

You may not qualify if…

• pregnancy or actively breastfeeding, weight instability (> or = to ± 5 lbs in the past month) evidence of cardiovascular or metabolic diseases, taking medications know to affect lipid and/or glucose metabolism.

Where it is running

• Michigan Clincal Research Unit — Ann Arbor, Michigan, United States

Full record on ClinicalTrials.gov

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