EoE(Eosinophilic Esophagitis)

Completed · Not applicable

Conditions studied: Eosinophilic Esophagitis, Dysphagia

In brief

To evaluate quantitative magnetic resonance imaging(MRI) as a potential non-invasive, radiation-free diagnostic tool for evaluating esophageal wall remodeling (thickness and stiffness) and response to treatment in children and adolescents with newly diagnosed eosinophilic esophagitis (EoE) presenting with dysphagia (difficulty swallowing) and food impaction.

Key facts

Study ID

NCT01999439

Run by

University of Michigan

People needed

10

Starts

2014-01-01

Expected to finish

2016-04-01

Last updated by the study team

2016-12-16

Who can join

Age: 8 and older, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Pediatric patients ages 8 to 18 years of age.
• Pediatric patients with dysphagia(difficulty swallowing) or an episode of food impaction.
• Pediatric patients newly diagnosed with Eosinophilic Esophagitis -

You may not qualify if…

• Are not able to undergo an MRI without needing sedation or general anesthesia
• Are allergic to gadolinium-based contrast material
• Have an ongoing acute kidney injury
• Have chronic kidney disease with an estimated glomerular filtration rate(eGFR)of <40 ml/min.
• Have a presence of eosinophilia involving the stomach and/or esophagus.
• Have a prior history of caustic ingestion
• Have a prior history of esophageal surgery, including history of tracheoesophageal fistula.
• Have known celiac disease
• Have known Crohn's disease
• Have known malignancy
• Have hypereosinophilic syndrome
• Have recent history of parasitic infection
• Have known inflammatory bowel disease -

Where it is running

• University of Michigan C. S. Mott Childrens Hospital — Ann Arbor, Michigan, United States

Full record on ClinicalTrials.gov

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