Simple Technique to Improve Diagnostic Yield in EUS-FNA

Completed · Not applicable

Conditions studied: Lesion Sampled for Cytology

In brief

Endoscopic ultrasound and fine needle aspiration are useful tools for the diagnosis and staging of pancreatic cancer. One potential limitation is contamination when needle traverses the gastrointestinal tract under continuous negative pressure. Gastrointestinal tract contamination can lead to misinterpretation of FNA specimens. We propose a technique to eliminate any remaining negative pressure during EUS-FNA and therefore decrease gastrointestinal tract contamination. Our hypothesis is that briefly untwisting the syringe from the biopsy channel after a specimen is obtained eliminates any remaining negative pressure in the FNA needle and therefore reduces GI tract contamination of EUS-FNA specimens, and will lead to improved diagnostic accuracy of this important clinical technique.

Key facts

Study ID

NCT01995474

Run by

Medical College of Wisconsin

People needed

60

Starts

2010-02-01

Expected to finish

2012-10-01

Last updated by the study team

2013-11-26

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age > 18
• Not pregnant
• Can give consent
• Patients with suspicious GI lesions in need of tissue diagnosis by means of EUS/FNA

You may not qualify if…

• Pregnant
• Age < 18
• Cannot give consent
• EUS not technically possible

Where it is running

• Medical College of Wisconsin — Milwaukee, Wisconsin, United States

Full record on ClinicalTrials.gov

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