Direct Comparison of 2D Cardiac PET With 3D Cardiac PET

Completed

Conditions studied: Coronary Artery Disease

In brief

Lowering the per-infusion dose of Rb-82 offers advantages of lessening radiation exposure and extending useable generator life. Prior studies have not shown equivalence of 3D vs 2D Rb-82 PET. The investigators therefore compare 3D PET after a lower Rb-82 dose (\~20 mCi) processed using a Monte-Carlo driven scatter correction algorithm against conventional higher dosage (\~50 mCi) 2D Rb-82 PET MPI.

Key facts

Study ID

NCT01993303

Run by

Cardiovascular Imaging Technologies

People needed

19

Starts

2004-01-01

Expected to finish

2012-06-01

Last updated by the study team

2013-11-25

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• >18 Years of Age
• Have ability to provide informed consent
• Have a technically adequate rest/stress Rb-82 perfsion PET study within the past 60 days

You may not qualify if…

• Pregnant or nursing feamle
• Weight > 275 lbs
• Have contraindications to adenosine stress testing
• Unstable cardiac rhythm (atrial fibrillation, frequent PVCs
• PTCA or CABG within the last 60 days

Where it is running

• Saint Lukes Hospital — Kansas City, Missouri, United States

Full record on ClinicalTrials.gov

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