Effect of Strawberries on Cardiovascular Disease Risk
Completed · Not applicable · Has a placebo group
Conditions studied: Cardiovascular Disease
In brief
It is important to identify and evaluate foods, such as strawberries, that can improve established and emerging cardiovascular risk factors, such as postprandial lipid and glycemic responses, and vascular health. Postprandial derangements may affect multiple metabolic pathways that lead to increased arterial stiffness. Research has demonstrated the potential of strawberries to ameliorate postprandial responses to a high fat/high glucose meal. Further research is needed to demonstrate this effect in better controlled clinical studies and explore whether metabolic effects lead to improved arterial health. The investigators propose to examine the effects of adding 40 g of freeze-dried strawberry powder to a high fat/high glucose meal on postprandial cardiovascular risk factor including lipids, insulin, glucose, and arterial stiffness and central blood pressure. The investigators hypothesize that the bioactive components of strawberry powder will attenuate postprandial lipemic and glycemic responses, as well as improve measures of arterial health.
Key facts
- Study ID
- NCT01989637
- Run by
- Penn State University
- People needed
- 34
- Starts
- 2013-07-01
- Expected to finish
- 2014-06-01
- Last updated by the study team
- 2023-08-21
Who can join
Age: 20 and older, up to 50. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- 20-50 years of age
- LDL-C below 160 mg/dL
- Triglycerides below 350 mg/dL
- No stage II hypertension (BP below 160/100 mmHg)
- Not taking medication for elevated lipids, blood pressure, or glucose
You may not qualify if…
- Allergies to strawberries
- Known intolerance to high fat meals
- History of cardiovascular disease, kidney disease, diabetes or inflammatory diseases such as GI disorders and arthritis
- Use of non-steroidal anti-inflammatory or immunosuppressant drugs
- Conditions requiring the use of steroids
- Use of medication or supplements for elevated lipids, blood pressure or glucose
Where it is running
- Penn State University — University Park, Pennsylvania, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.