Functional MRI Use in Prostate Radiation Treatment Planning
Completed · Not applicable
Conditions studied: Prostate Cancer
In brief
This study is being done to evaluate the use of MRI during radiation treatment planning to identify areas of tumor within the prostate to aid in future treatment planning and targeting of prostate cancer. This study will be conducted at the University of Pennsylvania Health System. The study is projected to run for 18 months. Subjects will be male 18 or older with a prostate cancer diagnosis and treatment plansat the Department of Radiation Oncology.
Key facts
- Study ID
- NCT01985932
- Run by
- Abramson Cancer Center at Penn Medicine
- People needed
- 15
- Starts
- 2012-07-01
- Expected to finish
- 2015-12-01
- Last updated by the study team
- 2019-11-26
Who can join
Age: 18 and older. Sex: male. Healthy volunteers: not accepted.
You may qualify if…
- Age 18 or older
- Male
- Biopsy proven prostate cancer without evidence of metastatic disease
- Planned definitive external beam RT with daily ERB and implanted Visicoil fiducial markers.
- Prior fMRI-ec documenting an IPL 25 mm2 in axial bidimensional diameter product, concordant with intraprostatic tumor location as documented on transrectal ultrasoundbiopsy
- Subject capable of giving informed consent for standard external beam RT and for the study.
- No current contraindication that would prevent MRI or gadolinium contrast.
You may not qualify if…
- Metastatic disease
- Lack of fMRI-ec documeneting an IPL 25 mm2 in axial bidimensional product, concordant with intraprostatic tumor location as documented on transrectal untrasound biopsy
- Neoadjuvant androgen deprivation therapy greater than 10 weeks, defined from date of LHRH analog injection to date of fMRI-sim
- Contraindication that would prevent MRI or gadolinium contrast
- GFR 30 mL/min/1.73m2 per Crockoft-Gault formula.
Where it is running
- Abramson Cancer Center of the University of Pennsylvania — Philadelphia, Pennsylvania, United States
Full record on ClinicalTrials.gov
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