DDAVP in the Reduction of Post-operative Ecchymosis in Rhinoplasty

Stopped early · Phase 2

Conditions studied: Postoperative Ecchymosis

In brief

This is study looking at the use of a medication, Desmopressin acetate (DDAVP), to reduce bleeding, swelling, and bruising in patients undergoing cosmetic nose surgery. DDAVP is a drug used in patients with bleeding disorders. It works by activating molecules in the blood stream called platelets that promote clotting. In the study, participants who are have cosmetic nose surgery (rhinoplasty) will be randomly assigned to receive or not receive medication. Photographs taken before and shortly after surgery will be evaluated for the amount of bruising and swelling. Patients with heart, lung, kidney, or liver problems are not eligible to participate.

Key facts

Study ID

NCT01982760

Run by

University Hospitals Cleveland Medical Center

People needed

14

Starts

2013-12-01

Expected to finish

2015-06-25

Last updated by the study team

2023-08-16

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Undergoing Rhinoplasty where nasal bone osteotomy is necessary

You may not qualify if…

• Heart Disease
• Renal Disease with decreased GFR
• Liver Disease

Where it is running

• Lyndhurst Surgery Center — Lyndhurst, Ohio, United States

Full record on ClinicalTrials.gov

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