Investigation of Immune Disorders and Deficiencies

Status unconfirmed

Conditions studied: Primary Immune Deficiencies, Autoimmune Diseases, Inflammatory Diseases, Common Variable Immune Deficiencies, Hypogammaglobulinemia

In brief

The immune system is an intricate system comprised of specialized cells, proteins, tissues and organs. Proper functioning is critical to the body's ability to defend itself against harmful pathogens. Immunological disorders and deficiencies are defects in the immune system that lead to abnormal immune responses. Abnormal immune responses could be derived from immune deficiencies, dysregulations or hypersensitivities. The overall goal of this research study is to identify the mechanisms of primary immune deficiencies and immune disorders at the genetic, cellular and molecular level, using novel analytic techniques to be performed on immune cells derived from blood samples. The knowledge gained from the aims of this study could lead to better diagnostics and identify novel targets for therapeutic interventions.

Key facts

Study ID: NCT01981785
Run by: O & O Alpan LLC
People needed: 343
Starts: 2012-12-01
Expected to finish: 2018-12-01
Last updated by the study team: 2017-04-04

Who can join

Age: 0 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

Subject is greater than or equal to 1 day of age and less than or equal to 100years of age
Signed Informed Consent/Assent
Subject is able and willing to comply with study protocol requirements
From clinical or blood laboratory findings subject has evidence of immune abnormalities (or no immune abnormalities in the case of controls) or immune-mediated disease.

You may not qualify if…

Risk factors for donating blood (such as anemia or blood clotting disorders)

Where it is running

O&O Alpan LLC — Fairfax, Virginia, United States

Full record on ClinicalTrials.gov

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