Efficacy of Buffered Lidocaine in Patients With Facial Swelling
Completed · Not applicable
Conditions studied: Orofacial Swelling
In brief
The purpose of this study is to determine the clinical efficacy of a buffered 4% lidocaine solution for incision and drainage. Ninety patients will be examined clinically to determine a diagnosis of cellulitis or fluctuance. The diagnosis will be confirmed by incision and drainage. Patients will receive either 3.6 ml 4% lidocaine with 1:100,000 epinephrine or 3.6 ml 4% lidocaine with 1:100,000 epinephrine buffered with 8.4% sodium bicarbonate. Patients will rate pain prior to and throughout the procedure.
Key facts
- Study ID
- NCT01981772
- Run by
- Ohio State University
- People needed
- 88
- Starts
- 2013-03-01
- Expected to finish
- 2014-06-01
- Last updated by the study team
- 2020-10-12
Who can join
Age: 18 and older, up to 100. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- 18 years or older
- in good health (ASA classification I or II)
- able to give informed consent
- necrotic tooth with associated facial swelling
You may not qualify if…
- allergies to local anesthetics or sulfites
- history of significant medical problems (ASA classification III or greater)
- pregnancy
- inability to give informed consent
Where it is running
- The Ohio State University College of Dentistry — Columbus, Ohio, United States
Full record on ClinicalTrials.gov
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