Detection and Neurological Impact of CerebroVascular Events In Noncardiac Surgery PatIents: A COhort EvaluatioN

Completed

Conditions studied: Covert Postoperative Stroke

In brief

The NeuroVISION Study will characterize the incidence, impact, and risk factors of covert stroke in adults undergoing noncardiac surgery. We will determine the incidence of acute covert stroke using an MRI study of the brain in the days following noncardiac surgery. We will characterize the epidemiology and the impact of covert stroke in patients undergoing noncardiac surgery, and its association with cerebral deoxygenation.

Key facts

Study ID

NCT01980511

Run by

McMaster University

People needed

1116

Starts

2014-03-24

Expected to finish

2018-11-06

Last updated by the study team

2019-01-10

Who can join

Age: 65 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥65 years old
• An anticipated hospital stay of at least 2 days after elective noncardiac surgery that occurs under general or neuraxial anesthesia
• Written informed consent for potential participation prior to noncardiac surgery

You may not qualify if…

• Contraindication to MRI (e.g. implanted devices not safe for MRI studies, claustrophobia)
• Unable or unwilling to attend the follow-up appointments
• Documented history of dementia
• Residing in a nursing home
• Undergoing carotid artery surgery or intracranial surgery
• Unable to complete neurocognitive testing due to language, vision or hearing impairment
• Unable to communicate with the research staff due to language barriers
• Patients who do not undergo their research MRI study after surgery
• Patients who do not complete a baseline MoCA questionnaire
• Patients who suffer an acute overt clinical stroke after the index surgery, but before their research MR study
• Previously enrolled in the NeuroVISION Study.

Where it is running

• University of Wisconsin — Madison, Wisconsin, United States
• St. Paul's Hospital — Vancouver, British Columbia, Canada
• Hamilton Health Sciences — Hamilton, Ontario, Canada
• University Hospital, London Health Sciences — London, Ontario, Canada
• Clinica Santa Maria — Providencia, Santiago Metropolitan, Chile
• Prince of Wales Hospital — Shatin, SAR, Hong Kong
• Narayana Health — Bangalore, India
• University Malaya Medical Centre — Kuala Lumpur, Malaysia
• Auckland City Hospital — Auckland, New Zealand
• Hospital Cayetano Heredia — Lima, Peru
• Szpital Specjalistycznym — Krakow, Poland

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.