Study of Icariin for Bipolar Disorder and Co-Occurring Substance Use Disorders

Completed · Phase 3

Conditions studied: Bipolar Disorder, Substance Use Disorder

In brief

This study is being done to see if icariin will help with depression in patients with bipolar disorder and alcohol or cocaine use disorders. The pills used in this study contain 20% icariin.

Key facts

Study ID

NCT01979133

Run by

University of Texas Southwestern Medical Center

People needed

10

Starts

2013-10-01

Expected to finish

2015-06-01

Last updated by the study team

2017-04-19

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Current BPD I, II or NOS and cocaine or alcohol use disorder with HAMD score of ≥ 15
• Cocaine or alcohol use with 5 days of initiating study drug
• Men and women
• Age 18-70 years

You may not qualify if…

• Psychotic features
• Non-English speakers
• Treatment resistant depression defined as failure of a trial of antidepressants (≥ 4 weeks at a therapeutic dose) in current episode
• Major medical condition including heart, lung, liver or renal disease, cancer, neurological or immunological conditions
• Vulnerable populations including prisoners, cognitively impaired individuals, and pregnant or nursing women
• Prior side effects or allergic reactions to icariin-containing preparations
• Change in psychotropic medications within 14 days of study entry
• Current suicidal ideation (plan and intent), a suicide attempt within the past 12 months or history of > 1 lifetime suicide attempt

Where it is running

• The University of Texas Southwestern Medical Center — Dallas, Texas, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.