A Pilot Study Testing Salicylic Acid Peels Versus Glycolic Acid Peels for the Treatment of Melasma

Running, not enrolling · Not applicable

Conditions studied: Melanosis

In brief

The purpose of this study is to find out the safety and effectiveness of Glycolic Acid Chemical Peels compared to Salicylic Acid Chemical Peels for the treatment of melasma.

Key facts

Study ID

NCT01976286

Run by

Northwestern University

People needed

21

Starts

2015-01-01

Expected to finish

2028-12-01

Last updated by the study team

2026-07-01

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Subjects aged 18 years or older
• Subjects with at least a 2 x 2 cm patch of melasma on each side of the face (forehead or cheek)
• Subjects in general good health
• Subjects must be willing and able to understand and provide informed consent for the use of their tissue and communicate with the investigator
• Subjects must be willing to not apply other treatment options for melasma during the course of the study

You may not qualify if…

• Subjects under 18 years of age
• Subjects who are pregnant and/or lactating
• Subjects who are unable to understand the protocol or to give informed consent
• Subjects diagnosed with mental illness
• Subjects who have concurrent active uncontrolled disease to facial area (i.e uncontrolled acne)
• Subjects who have had a chemical peel in the past 3 months
• Subjects who have used a prescribed retinoid in the past 3 months
• Subjects with a bleeding disorder
• Subjects with a history of abnormal wound healing
• Subjects with a history of abnormal scarring

Where it is running

• Northwestern University Department of Dermatology — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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