Laser Therapy Treatment of Peri-implantitis.

Withdrawn before enrolling · Phase 3

Conditions studied: Peri-implantitis

In brief

The primary objective of this study is to compare the clinical outcomes of using Er: YAG laser along with bone graft and barrier membrane to conventional mechanical debridement also with bone graft and barrier membrane in the treatment of peri-implantitis infections.

Key facts

Study ID

NCT01972399

Run by

University of Michigan

People needed

0

Starts

2016-01-01

Last updated by the study team

2015-04-03

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patients, aged 18 - 85 years
• Physical status according to the American Society of Anesthesiologists (ASA) I or II, which includes patients who are systemically healthy or suffer under mild to moderate, but well controlled systemic diseases.
• Patients having a minimum of 1 dental implant with peri-implantitis.
• The dental implant with peri-implantitis has ≥ 3 threads exposed or pocket probing depth (PPD) ≥ 5mm, with bleeding on probing (BOP) and/or suppuration (pus).
• The implants are in function for at least 6 months
• No uncontrolled systemic disease or condition known to alter bone metabolism, like Osteoporosis, Osteopenia, Hyperparathyroidism, Paget's disease.
• Only rough surface implant will be included in this study

You may not qualify if…

• Long-term use of antibiotics > 2 weeks in the past two months
• No peri-implantitis treatment in the last 2 months
• Patients taking medications known to modify bone metabolism (such as bisphosphonates, corticosteroids, Hormone replacement therapy for menopausal women, Parathyroid hormone, Denosumab, strontium ranelate).
• Pregnant females or those planning to become pregnant.
• Patients with a history of medically diagnosed oral cancer, bisphosphonate usage, Sepsis or those having adverse outcomes to oral procedures in the past, will be excluded
• Mobility of dental implants
• History of alcoholism or drug abuse
• Current smokers or quit smoking less than 6 months
• Diseases of the immune system or any medical condition that may influence the outcome (uncontrolled diabetes (HbA1c >7)
• Patients with allergies known to affect one or more of the treatment provided in this study
• Polish surface implants
• Implants with trabecular surface

Where it is running

• University of Michigan School of Dentistry — Ann Arbor, Michigan, United States

Full record on ClinicalTrials.gov

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