An Extension Study of ABT-199 in Subjects With Advanced Non-Hodgkin's Lymphoma
Completed · Phase 1
Conditions studied: Non-Hodgkin's Lymphoma
In brief
This is a Phase 1, open-label, multicenter, extension study. Subjects with non-Hodgkin's lymphoma (NHL) (excluding chronic lymphocytic lymphoma \[CLL\], small lymphocytic lymphoma \[SLL\], and mantle cell lymphoma \[MCL\]) who completed a prior ABT-199 study, or were active and assigned to ABT-199 when the study was completed, may roll over into this extension study. Subjects will receive ABT-199 during this study.
Key facts
- Study ID
- NCT01969695
- Run by
- AbbVie
- People needed
- 11
- Starts
- 2013-12-20
- Expected to finish
- 2019-12-16
- Last updated by the study team
- 2019-12-19
Who can join
Age: 18 and older, up to 99. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Subject has completed a prior ABT-199 study (and had met the criteria for a diagnosis of NHL and all other eligibility criteria for the previous study) and the investigator believes that treatment with ABT-199 is in the best interest of the subject.
You may not qualify if…
- Subject discontinued ABT-199 administration before completing the prior study (due to disease progression, toxicity, withdrawn consent, other).
- Subject has any medical condition that in the opinion of the investigator places the subject at an unacceptably high risk for toxicities.
- Subject has not recovered to ≤ Grade 2 clinically significant adverse effect(s)/toxicity(ies) of previous therapy.
- Subject has been diagnosed with Post-Transplant Lymphoproliferative Disease (PTLD), Burkitt's lymphoma, Burkitt-like lymphoma, lymphoblastic lymphoma/leukemia, chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), or mantle cell lymphoma (MCL).
Where it is running
- University of Arizona Arthritis Center /ID# 101359 — Tucson, Arizona, United States
- Dartmouth-Hitchcock Med Ctr /ID# 92596 — Lebanon, New Hampshire, United States
- Hackensack Univ Med Ctr /ID# 101417 — Hackensack, New Jersey, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.