NCGENES: North Carolina Clinical Genomic Evaluation by NextGen Exome Sequencing

Completed · Not applicable

Conditions studied: Cancer, Cardiovascular Disease, Neurologic Dysfunction, Congenital Abnormalities, Hearing Loss

In brief

This study is part of a larger consortium project investigating the validity and best use of next-generation sequencing (in particular, whole exome sequencing, or WES) in clinical care. This sub-project is investigating benefits and harms of providing WES diagnostic and different types of incidental findings to adult patients and parents of pediatric patients who undergo WES because they have symptoms suggesting genetic disease.

Key facts

Study ID
NCT01969370
Run by
University of North Carolina, Chapel Hill
People needed
645
Starts
2012-08-01
Expected to finish
2017-03-01
Last updated by the study team
2017-05-03

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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