ASPREE Cancer Endpoints Study
Status unconfirmed · Phase 4 · Has a placebo group
Conditions studied: Cancer
In brief
The ASPREE Cancer Endpoint Study (ACES), an ancillary study of the ASPirin in the Prevention of Events in the Elderly (ASPREE) Study, will allow for the examination of the effect of daily low-dose aspirin (100 mg) compared to placebo, on specific DNA biomarkers and selected specific incident and recurrent cancer and metastases. The establishment of this ACES biobank will allow for the exploration of DNA-related molecular mechanisms of aspirin's protective effect against cancer, cancer associated mortality and metastases, using blood or saliva DNA specimens, urine, and tumor tissue.
Key facts
- Study ID
- NCT01968798
- Run by
- Hennepin Healthcare Research Institute
- People needed
- 14500
- Starts
- 2013-09-01
- Expected to finish
- 2024-04-01
- Last updated by the study team
- 2021-04-05
Who can join
Age: 65 and older. Sex: any. Healthy volunteers: accepted.
Where it is running
- The University of Alabama at Birmingham — Birmingham, Alabama, United States
- Palo Alto Medical Foundation Research Institute — Palo Alto, California, United States
- Howard University — Washington D.C., District of Columbia, United States
- University of Florida Department of Aging and Geriatrics — Gainesville, Florida, United States
- Morehouse School of Medicine — Atlanta, Georgia, United States
- Emory/ Atlanta VAMC — Atlanta, Georgia, United States
- Georgia Health Sciences University — Augusta, Georgia, United States
- Rush Alzheimer's Disease Center — Chicago, Illinois, United States
- University of Iowa — Iowa City, Iowa, United States
- Kansas University Medical Center — Kansas City, Kansas, United States
- Baton Rouge General — Baton Rouge, Louisiana, United States
- Pennington Biomedical Research Center — Baton Rouge, Louisiana, United States
- Mary Bird Perkins Our Lady of the Lake Cancer Center — Baton Rouge, Louisiana, United States
- Mary Bird Perkins St. Tammany Parish Hospital — Covington, Louisiana, United States
- Mary Bird Perkins Terrebonne General Hospital — Houma, Louisiana, United States
- LSU Health Sciences- New Orleans — New Orleans, Louisiana, United States
- Tulane Medical Center — New Orleans, Louisiana, United States
- LSU Health Sciences- Shreveport — Shreveport, Louisiana, United States
- University of Michigan — Ann Arbor, Michigan, United States
- Wayne State University — Detroit, Michigan, United States
- Henry Ford Health System — Detroit, Michigan, United States
- Detroit Clinical Research Center — Novi, Michigan, United States
- HealthPartners Research Institute — Minneapolis, Minnesota, United States
- Phalen Village Clinic — Saint Paul, Minnesota, United States
- Central Jersey Medical Center — Elizabeth, New Jersey, United States
Full record on ClinicalTrials.gov
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