Predictors of Respiratory Failure Following Extubation in the SICU

Status unconfirmed

Conditions studied: Muscle Weakness, Renal Failure, Respiratory Comorbidities

In brief

Respiratory failure following extubation causes significant morbidity and increases mortality in teh surgical intensive care unit (SICU). However the causes of respiratory failure following extubation remain poorly understood. The investigators hypothesize that extubation failure can be predicted based on preoperative risk factors as well as ICU acquired morbidities including muscle weakness and renal failure.

Key facts

Study ID

NCT01967056

Run by

Massachusetts General Hospital

People needed

750

Starts

2013-06-01

Expected to finish

2014-10-01

Last updated by the study team

2013-10-22

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults (18 years of age or greater)
• Patients who have been extubated following mechanical ventilation in the surgical ICU

You may not qualify if…

• Preexisting end-stage renal disease
• Neurological disorder associated with severe muscle weakness
• Goals of care focused on comfort

Where it is running

• Massachusetts General Hospital — Boston, Massachusetts, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.