Effect of Sildenafil on Diffusion Capacity in Patients With PH and Parenchymal Lung Disease

Completed · Not applicable

Conditions studied: Diffuse Parenchymal Lung Disease, Pulmonary Hypertension

In brief

The purpose of this study was to investigate the acute effects of sildenafil on diffusion capacity, a commonly performed pulmonary function test, which is used to assess the lungs' gas exchange capability. This study does not assess safety or efficacy of the drug. The study does not have clinical end points. The variables studied are diffusion capacity and 6 minute walk after a single dose of sildenafil. This study has been completed.

Key facts

Study ID

NCT01948518

Run by

The Cleveland Clinic

People needed

15

Starts

2009-06-01

Expected to finish

2012-06-01

Last updated by the study team

2014-09-30

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patients over age 18 years of age who are able to consent
• Diagnosis of diffuse parenchymal lung disease with concomitant pulmonary hypertension

You may not qualify if…

• None

Where it is running

• Cleveland Clinic — Cleveland, Ohio, United States

Full record on ClinicalTrials.gov

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