The Effects of Ankle Foot Orthoses (AFOs) on Mobility in Persons With Multiple Sclerosis (MS)

Completed · Not applicable

Conditions studied: Multiple Sclerosis

In brief

The purpose of this study is to investigate the impact of ankle foot orthoses (AFOs) on the spatial and temporal gait parameters, electromyography (EMG), walking endurance, and quality of life in select individuals living with MS. The hypotheses of the study are: 1. Individuals who are fit with an AFO will demonstrate improvements in spatial and temporal gait parameters 2. Individuals who are fit with an AFO will demonstrate improvements in walking endurance. 3. Individuals who are fit with an AFO will demonstrate improvements in muscle firing profiles/EMG measures. 4. Individuals who are fit with an AFO will demonstrate improvements in quality of life.

Key facts

Study ID

NCT01947582

Run by

University of Texas Southwestern Medical Center

People needed

2

Starts

2013-10-01

Expected to finish

2014-12-01

Last updated by the study team

2016-03-07

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Individuals with a primary diagnosis of multiple sclerosis
• Individuals who are able to maintain a walking velocity of 30 cm/sec for at least 2 minutes independently or with the use of a single tip assistive device.
• Could have current or past history of single or bilateral AFO use, including neuroprostheses
• Evidence of weakness in plantarflexors

You may not qualify if…

• The presence of co-morbidities (neuromuscular or musculoskeletal) that would negatively impact gait training
• Individuals with BMI with >/= 40kg/m2
• Individuals with range of motion deficit in the ankle limiting passive range of motion to neutral dorsiflexion
• Individuals that plan to begin the use of Ampyra during the course of the study
• Individuals for whom the cost of an orthosis would represent a financial burden
• Individuals who are receiving concurrent physical therapy services elsewhere
• MSNQ of >22

Where it is running

• UT Southwestern Medical Center School of Health Professions — Dallas, Texas, United States

Full record on ClinicalTrials.gov

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