Intraoperative Lidocaine Infusion for Postoperative Pain Management in Obese Patients

Completed · Phase 3 · Has a placebo group

Conditions studied: Bariatric Surgical Pain

In brief

The primary objective is to assess the feasibility and safety of administering continuous intraoperative lidocaine infusions in adult patients undergoing laparoscopic Roux en Y Gastric Bypass (RYGB). The secondary objective is to determine if lidocaine administration versus placebo (dextrose administration) (initiated at the time of anesthesia induction and continued until extubation) will reduce postoperative narcotic requirements.

Key facts

Study ID

NCT01944098

Run by

University of South Florida

People needed

20

Starts

2013-08-01

Expected to finish

2014-09-01

Last updated by the study team

2017-10-26

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patients between the ages of 18-65 years old
• BMI ≥ 40 kg/m2, ≤ 60 kg/m2
• Undergoing a primary laparoscopic RYGB by Dr. Murr
• Agree to be followed 24 hours postoperatively
• Normal K+ and Mg++ serum levels

You may not qualify if…

• BMI less than 40 kg/m2, > 60 kg/m2
• Laparoscopic RYGB surgery performed by a surgeon other than Dr. Murr
• Allergy to lidocaine
• Allergy to hydromorphone or ketorolac
• Allergy to corn or amide anesthetics
• Use of (thioridizine)
• Pregnancy
• Abnormalities of ALT or AST
• Intra-operative diagnosis of cirrhosis or portal hypertension
• Intraoperative complications per surgeon
• Intraoperative extensive adhesions per surgeon
• Chronic pain syndrome and chronic use of narcotics
• Severe back pain secondary to degenerative joint disease

Where it is running

• Tampa General Hospital — Tampa, Florida, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.