A Study of the Effect of BIIB023 on Muscle Atrophy in Healthy Male Volunteers

Completed · Phase 1 · Has a placebo group

Conditions studied: Healthy

In brief

The primary objective of this study is to determine whether muscle atrophy induced by immobilization of the lower limb can be attenuated by BIIB023 in healthy male volunteers. The secondary objectives of this study in this study population are: * To determine whether muscle weakness induced by immobilization of the lower limb can be attenuated by BIIB023 * To assess the effect of BIIB023 on the recovery of muscle mass and strength after immobilization * To assess the effect of BIIB023 on histological markers of muscle atrophy and regeneration * To assess the effect of BIIB023 on muscle bioenergetics based on oxidative metabolism recovery kinetics * To evaluate the safety and tolerability of BIIB023

Key facts

Study ID
NCT01943513
Run by
Biogen
People needed
34
Starts
2013-10-01
Expected to finish
2014-05-01
Last updated by the study team
2014-09-03

Who can join

Age: 18 and older, up to 35. Sex: male. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.