High-Dose Trivalent Influenza Vaccine in Inducing Immune Response Patients With Central Nervous System Tumors
Completed · Phase 1
Conditions studied: Central Nervous System Neoplasm
In brief
This pilot clinical trial studies high-dose trivalent influenza vaccine in inducing immune response patients with central nervous system tumors. Studying samples of blood in the laboratory from patients receiving trivalent influenza vaccine may help doctors learn more about the effects of trivalent influenza vaccine on cells. It may also help doctors understand how well patients respond to treatment.
Key facts
- Study ID
- NCT01941758
- Run by
- Wake Forest University Health Sciences
- People needed
- 28
- Starts
- 2013-11-01
- Expected to finish
- 2014-11-01
- Last updated by the study team
- 2018-07-05
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients must have a clinical diagnosis of a primary central nervous system tumor
- Patients must be eligible to receive the influenza vaccine
- Patients must be willing to receive the Fluzone® high-dose seasonal influenza vaccine
- Patients must be willing and able to sign an Institutional Review Board (IRB)-approved written informed consent document
You may not qualify if…
- Patients unable to receive the high-dose influenza vaccine due to history of allergy to egg proteins, allergy to influenza vaccine component, acute febrile illness at the time of proposed vaccine administration, history of clinically or virologically confirmed influenza infection in the previous 6 months, contraindication to intramuscular injections, Guillain-Barré syndrome, or other contraindication to the vaccine
- Patients who have received the 2013-2014 annual influenza vaccine prior to being considered for enrollment on this study
Where it is running
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Hospital — Baltimore, Maryland, United States
- Comprehensive Cancer Center of Wake Forest University — Winston-Salem, North Carolina, United States
Full record on ClinicalTrials.gov
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