DBS Frequency on Swallowing Function in Parkinson's Disease

Completed

Conditions studied: Parkinson's Disease

In brief

The stimulation frequency has been found to affect the axial symptoms of freezing of gait (FOG) and speech in advanced Parkinson's disease (PD) patients with subthalamic nucleus deep brain stimulation (STN DBS), with the traditionally high stimulation frequency of 130 Hz worsening while low frequency of 60 Hz improving these symptoms. The effect of stimulation frequency on another important axial symptom, swallowing dysfunction, has not been studied. The investigators hypothesize that stimulation frequency could have similar effect on swallowing function.

Key facts

Study ID

NCT01935011

Run by

University of Chicago

People needed

7

Starts

2013-08-01

Expected to finish

2014-07-01

Last updated by the study team

2015-04-28

Who can join

Age: 45 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Eight PD patients with STN DBS and freezing of gait responsive to stimulation frequency changes will be enrolled.

You may not qualify if…

• Patients who do not meet the inclusion criteria

Where it is running

• University of Chicago — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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