A Pilot Study on the Use of Prophylactic Antibiotics for EUS-guided Pancreatic Cyst Aspiration

Completed · Not applicable · Has a placebo group

Conditions studied: Pancreatic Cysts

In brief

Our hypothesis is that a single dose of antibiotics at time of EUS-guided pancreatic cyst aspiration is equally effective to the usual regimen of 3 days of post-procedural antibiotics.

Key facts

Study ID

NCT01929460

Run by

Kaiser Permanente

People needed

26

Starts

2014-01-01

Expected to finish

2014-11-01

Last updated by the study team

2016-02-15

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients between the age of 18-90 who present for an EUS / pancreas cyst evaluation

You may not qualify if…

• Patients outside the age range
• Patient-related factors (unable to provide consent, unable to understand English, allergic to cipro)
• High-risk patients for infective endocarditis
• Bacterial infection or use of antibiotics within 6 weeks of EUS
• Pancreatitis within the past 6 months
• Underlying immunosuppression (for example, uncontrolled diabetes - such as hemoglobin A1c above 7 or glucose > 180; renal failure; cirrhosis; pre-existing malignancy especially hematologic malignancy such as leukemia / lymphoma / multiple myeloma; HIV/AIDS)
• Currently taking immunosuppressive medications (for conditions such as rheumatoid arthritis, inflammatory bowel disease, organ transplant)
• Radiographic or endosonographic evidence of cyst cavity debris / necrotic debris
• Severe systemic disease (for example, NYHA class III or IV heart failure, oxygen-dependent COPD)

Where it is running

• Kaiser Permanente, Los Angeles Medical Center — Los Angeles, California, United States

Full record on ClinicalTrials.gov

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