Telmisartan to Reduce AIDS-Related Fibrotic and Inflammatory Contributors (TRAFIC Study)
Completed · Phase 2
Conditions studied: HIV-1 Infection
In brief
The main goal of this study was to see if a drug called telmisartan would decrease fibrosis (scarring) and inflammation (irritation) in people who are infected with HIV and doing well on their HIV medications. The study was also done to see what effects telmisartan has on other signs of disease and inflammation in the body, and to see whether people who have HIV can take telmisartan safely and without side effects that make them want to stop the drug. Telmisartan is FDA-approved for treating high blood pressure and decreasing the chance of heart attacks and strokes in people over the age of 55 years of age who are at high risk for these events.
Key facts
- Study ID
- NCT01928927
- Run by
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
- People needed
- 58
- Starts
- 2014-01-01
- Expected to finish
- 2016-03-01
- Last updated by the study team
- 2021-08-03
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- UCLA CARE Center CRS (601) — Los Angeles, California, United States
- University of Colorado Hospital CRS (6101) — Aurora, Colorado, United States
- Massachusetts General Hospital ACTG CRS (101) — Boston, Massachusetts, United States
- Washington U CRS (2101) — St Louis, Missouri, United States
- University of Rochester Adult HIV Therapeutic Strategies Network CRS (31787) — Rochester, New York, United States
- Unc Aids Crs (3201) — Chapel Hill, North Carolina, United States
- Univ. of Cincinnati CRS (2401) — Cincinnati, Ohio, United States
- Case CRS (2501) — Cleveland, Ohio, United States
- Vanderbilt Therapeutics CRS (3652) — Nashville, Tennessee, United States
- Houston AIDS Research Team CRS (31473) — Houston, Texas, United States
- University of Washington AIDS CRS (1401) — Seattle, Washington, United States
- Puerto Rico-AIDS CRS (5401) — San Juan, Puerto Rico
Full record on ClinicalTrials.gov
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