Perfusion Assessment of Wound Closure Techniques in Primary Total Knee Arthroplasty

Completed · Not applicable

Conditions studied: Total Knee Arthroplasty

In brief

This study will assess which of the three most common methods of wound closure in primary total knee arthroplasty (staples, interrupted vertical mattress, or running subcuticular suture) provide the best wound vascular perfusion. This can be achieve by using SPY intra-operative vascular angiography, which is commonly used in clinical practice to assess perfusion of wound closure at the clinic. By understanding the differences in perfusion afforded by different closure techniques, surgeons will then be able to select the technique that optimizes this parameter so as to avoid complications such as tissue necrosis, wound dehiscence, or infection.

Key facts

Study ID

NCT01924403

Run by

Mayo Clinic

People needed

45

Starts

2013-08-01

Expected to finish

2014-07-01

Last updated by the study team

2015-02-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• ≥ 18 years old
• Primary diagnosis of osteoarthritis
• Surgical indication for index total knee arthroplasty

You may not qualify if…

• Previous surgery about the knee
• Systemic corticosteroid use
• Active infection of any kind or chronic infection with HIV, Hepatitis C, or Syphilis

Where it is running

• Mayo Clinic in Rochester — Rochester, Minnesota, United States

Full record on ClinicalTrials.gov

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