Postprandial Response to Almond Consumption in Overweight Hispanic Pregnant Women
Completed · Not applicable
Conditions studied: Diabetes, Gestational
In brief
Currently, about one third of all women entering pregnancy are obese. The prevalence of metabolic disorders during pregnancy has increased concurrently with the rise in maternal obesity. Although dietary interventions are used routinely to reduce metabolic disease in non-pregnant obese individuals, no specific dietary advice is provided to obese, pregnant women unless they develop gestational diabetes mellitus. In this study, the investigators will specifically assess the effect of replacing dairy fats with almonds in a breakfast meal on the postprandial metabolic response. This cross-over, randomized control trial will examine the postprandial metabolic response to 0 or 2 oz of almonds in standardized test meals in pregnant Hispanic women with prepregnancy BMI between 25 and 40. Hispanics are at higher risk for gestational diabetes and the metabolic syndrome. The investigators hypothesize that consuming almonds in place of dairy fat reduces the glycemic response and improves the postprandial lipid profile in these high-risk women.
Key facts
- Study ID
- NCT01919476
- Run by
- UCSF Benioff Children's Hospital Oakland
- People needed
- 18
- Starts
- 2011-09-01
- Expected to finish
- 2016-03-01
- Last updated by the study team
- 2020-11-24
Who can join
Age: 19 and older, up to 40. Sex: female. Healthy volunteers: accepted.
You may qualify if…
- Pregnant Hispanic women
- Between 30 and 36 weeks gestation
- Prepregnancy BMI between 25 and 40
You may not qualify if…
- Diagnosis of gestational diabetes mellitus
- Preexisting diabetes mellitus
- Renal disease
- Thyroid disease
- Cardiovascular disease
- History of drug abuse
- Nut allergies
Where it is running
- Children's Hospital Oakland Research Institute — Oakland, California, United States
Full record on ClinicalTrials.gov
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