The Valve of Hyaluronic Binding Selection (PICSI) in Improving IVF Outcome

Completed · Not applicable

Conditions studied: Infertility

In brief

The investigators would like to assess whether selecting mature sperm using PICSI (selecting for sperm that bind hyaluronan) can optimize the IVF outcome of ICSI . Aim 1. Primary outcome: To compare routine sperm selection using ICSI with sperm selection using PICSI plates in terms of implantation and fertilization rates for couples with male factor fertility 2. Secondary outcome : To compare live birth rates ,ongoing pregnancies and miscarriage rates for couples with male factor infertility using routine sperm selection with ICSI compared to using PICSI plates for sperm selection Hypothesis: Sperm selected for ICSI using (PICSI) will reveal increased implantation rates in comparison to sperm selected for conventional ICSI

Key facts

Study ID

NCT01916213

Run by

St. Luke's-Roosevelt Hospital Center

People needed

30

Starts

2013-03-01

Expected to finish

2014-06-01

Last updated by the study team

2015-10-14

Who can join

Age: 18 and older, up to 42. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• In order to participate in the study women must be 42 years old or younger and suffer from male factor infertility however they may have other causes for their infertility
• male factor infertility as defined by one or more of the following sperm parameters: <20 Million /ml sperm concentration < 30% normal morphology < 3% Kruger morphology < 50% motility sion Criteria:

Where it is running

• Continuum Reproductive Center — New York, New York, United States

Full record on ClinicalTrials.gov

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