Clinical Research Study to Evaluate Selegiline in the Treatment of Borderline Personality Disorder

Completed · Phase 3 · Has a placebo group

Conditions studied: Borderline Personality Disorder

In brief

Selegiline is superior to placebo in improving psychological and physical functioning in patients with Borderline Personality Disorder.

Key facts

Study ID

NCT01912391

Run by

Mood and Anxiety Research, Inc

People needed

30

Starts

2012-10-01

Expected to finish

2015-03-01

Last updated by the study team

2015-10-08

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Subject has primary diagnosis of Borderline Personality Disorder(BPD).
• Subject has Symptomatology of BPD for at least 1 year.
• Subject understands the study procedures and voluntarily agree to participate.
• Subject is able to read, understand and complete questionnaires.
• Subject agrees to use (2)acceptable forms of contraception throughout the study.
• Patient must have a screening SCL 90-R score of > 120 (range 0-360).

You may not qualify if…

• Subject is not pregnant or breast feeding.
• Subject is unlikely to adhere to the study procedures and restrictions.
• Patient has failed treatment due to lack of efficacy of monoamine oxidase inhibitor(MAOI) medication.
• Patient anticipates need for surgery during the study.
• Patient has another predominant personality disorder other than BPD.
• Subject has an active history of substance abuse or dependence, e.g.,Positive Drug screen
• Subject has other health issues which could interfere with study interpretation.
• Subject reports recent suicide attempts or homicide attempts in the past 3 months.
• Subject must be substance abuse or dependence clean for (1) year.
• Subject has a history of a primary malignancy < 5 yrs.
• Subject has a medical condition(s)that are excluded, per Protocol, or are unstable.
• Subject has abnormal screening laboratory values, per Protocol, or other clinically significant, unexplained laboratory abnormality.
• Subject is currently participating or has participated in a study within 30 days.
• Patient has donated blood products or has had phlebotomy of > 300 ml within 8 weeks.

Where it is running

• Mood and Anxiety Research, Inc — Fresno, California, United States

Full record on ClinicalTrials.gov

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