Sickle Cell Anemia - A Comparative Study Between Three Ethnical Communities, a Multicenter Study

Status unconfirmed

Conditions studied: Sickle Cell Anemia, Sickle Cell β+ or β0 Thalassemia

In brief

The purpose of this study is to take advance of the presence of two different cohorts of SCA patients in one country, the first group included SCA patients from Bedouin Arab origin that lives in Israel for more than one century and originally comes from African countries or Saudi Arabia, those patients lives in north east Israel and are treated at the Hematology Unit of the Emek Medical Center, the second group are SCA patients from African origin that come to Israel in the last decades and belong to original African population, this group receive treatment at the Pediatric Hematology Unit, Dana Children's Hospital, Ichilov Medical Center. A third group is a cohort of SCA patients treated at Schneider Children's Hospital Hematology Unit. Those patients belong also to the Israel Arab population and patients from a village that African Muslims live for many years. The characteristics of the three groups will be compared to the characteristics of a fourth group, a cohort of Afro-American SCA patients that are followed up and treated at the Pediatric Hematology Unit, Detroit Children's Medical Center, Detroit, Michigan, USA.

Key facts

Study ID

NCT01905787

Run by

HaEmek Medical Center, Israel

People needed

300

Starts

2012-01-01

Expected to finish

2020-12-31

Last updated by the study team

2019-10-31

Who can join

Age: 1 and older, up to 40. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• All patients followed up in the centers that participate in the study.
• Pregnancy will not be considered as exclusion criteria.

You may not qualify if…

• Patients with SC and SD disease will not be included.

Where it is running

• Children's Hospital of Michigan, Detroit Medical Center - Wayne State University — Detroit, Michigan, United States
• Pediatric Hematology Unit HaEmek Medical Center — Afula, Israel
• Pediatric Hematology Unit - Schneider Children's Hospital - Beilinson Medical Center — Petah Tikva, Israel
• Pediatric Hematology Unit - Dana Children's Hospital - Ichilov Medical Center — Tel Aviv, Israel

Full record on ClinicalTrials.gov

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