Registry Study of T Cell Depleted Allo Non-Myeloablative Stem Cell Transplant

Completed

Conditions studied: Hodgkin's Disease, Non Hodgkin's Lymphoma, Myeloma, Leukemia, Myelodysplasia

In brief

Allogeneic transplantation is used to treat many malignant and non-malignant diseases. The investigators and others have shown that less toxic preparative regimens (reduced intensity or 'mini' transplants) allow reliable allogeneic engraftment and durable remissions, significantly broadening the population of patients who may be offered this therapy to those who are older and more infirmed. The field is now focusing on the period post transplant for approaches to immune recovery leading to improved outcomes. The primary objective of this registry is to catalogue data from patients who undergo standard of care reduced intensity allogeneic transplantation.

Key facts

Study ID

NCT01904175

Run by

Duke University

People needed

48

Starts

2013-08-01

Expected to finish

2016-04-01

Last updated by the study team

2016-05-05

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may not qualify if…

• Subjects < 18 years of age
• Subjects not undergoing nonmyeloablative or ablative allogeneic transplant

Where it is running

• Duke University Health System — Durham, North Carolina, United States

Full record on ClinicalTrials.gov

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