CPT and Smoking Cessation

Completed · Phase 2/Phase 3

Conditions studied: Stress Disorders, Post-Traumatic, Smoking

In brief

Posttraumatic stress disorder (PTSD) and cigarette smoking are both associated with significant impairment in Veterans and cost to the Veterans' Affairs (VA) system. Though research suggests smoking is linked with PTSD symptoms, existing smoking cessation treatments targeting PTSD smokers do not include PTSD treatment. The purpose of this study is to examine a treatment that combines evidence based treatment for PTSD (cognitive processing therapy, or CPT) with smoking cessation treatment for PTSD and a mobile text messaging program. The study objectives are to evaluate feasibility of the treatment and to examine effectiveness of CPT and smoking cessation treatment combined compared to smoking cessation treatment without CPT. Fifty Veteran smokers with PTSD will participate in fourteen study sessions, ending with the final follow-up session six months after the scheduled quit date.

Key facts

Study ID

NCT01901848

Run by

VA Office of Research and Development

People needed

69

Starts

2013-12-11

Expected to finish

2017-07-30

Last updated by the study team

2018-09-11

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Must be U.S. Veteran
• Smoke at least ten cigarettes a day
• Meet criteria for current PTSD
• Speak and write fluent conversational English
• Be between 18 and 65 years of age
• Be willing to attempt smoking cessation
• Must have access to a phone capable of receiving text messages

You may not qualify if…

• Not stable on medications for the study period
• History of myocardial infarction in the past 6 months
• Contraindication to NRT and inability to get medical clearance from primary care provider
• Use of other forms of nicotine such as cigars, pipes, or chewing tobacco.
• Pregnancy
• Inability to complete study measures and tasks independently
• Dementia or other brain disorder, schizophrenia, current manic syndrome, or substance abuse/dependence in the preceding 3 months.
• Currently receiving trauma-focused psychotherapy.
• Currently living in court-ordered residential substance abuse treatment.

Where it is running

• Durham VA Medical Center, Durham, NC — Durham, North Carolina, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.