Comparison of Axillary Lymph Node Dissection With Axillary Radiation for Patients With Node-Positive Breast Cancer Treated With Chemotherapy
Running, not enrolling · Phase 3
Conditions studied: Stage II Breast Cancer, Stage IIIA Breast Cancer
In brief
This randomized phase III trial studies lymph node dissection and radiation therapy to see how well it works compared to radiation therapy alone in treating patients with breast cancer previously treated with chemotherapy and surgery. Lymph node dissection may remove cancer cells that have spread to nearby lymph nodes in patients with breast cancer. Radiation therapy uses high-energy x rays or protons to kill tumor cells. It is not yet known if radiation therapy works better alone or with lymph node dissection in treating patients with breast cancer previously treated with chemotherapy and surgery.
Key facts
- Study ID
- NCT01901094
- Run by
- Alliance for Clinical Trials in Oncology
- People needed
- 2012
- Starts
- 2014-02-24
- Expected to finish
- 2031-01-31
- Last updated by the study team
- 2026-07-23
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Mobile Infirmary Medical Center — Mobile, Alabama, United States
- Southern Cancer Center PC-Mobile — Mobile, Alabama, United States
- Southern Cancer Center PC-Providence — Mobile, Alabama, United States
- Southern Cancer Center PC-Springhill — Mobile, Alabama, United States
- University of South Alabama Mitchell Cancer Institute — Mobile, Alabama, United States
- Anchorage Associates in Radiation Medicine — Anchorage, Alaska, United States
- Anchorage Radiation Therapy Center — Anchorage, Alaska, United States
- Alaska Breast Care and Surgery LLC — Anchorage, Alaska, United States
- Alaska Oncology and Hematology LLC — Anchorage, Alaska, United States
- Alaska Regional Hospital — Anchorage, Alaska, United States
- Alaska Women's Cancer Care — Anchorage, Alaska, United States
- Anchorage Oncology Centre — Anchorage, Alaska, United States
- Katmai Oncology Group — Anchorage, Alaska, United States
- Providence Alaska Medical Center — Anchorage, Alaska, United States
- Fairbanks Memorial Hospital — Fairbanks, Alaska, United States
- Arizona Breast Cancer Specialists-Gilbert — Gilbert, Arizona, United States
- Virginia G Piper Cancer Care-Glendale — Glendale, Arizona, United States
- Arizona Center for Cancer Care-Peoria — Peoria, Arizona, United States
- Cancer Center at Saint Joseph's — Phoenix, Arizona, United States
- Arizona Breast Cancer Specialists-Phoenix — Phoenix, Arizona, United States
- Arizona Breast Cancer Specialists — Scottsdale, Arizona, United States
- Arizona Breast Cancer Specialists-Scottsdale — Scottsdale, Arizona, United States
- Virginia G Piper Cancer Care-Del Camino — Scottsdale, Arizona, United States
- Arizona Center for Cancer Care-Surprise — Surprise, Arizona, United States
- Southern Cancer Center PC-Daphne — Daphne, Alabama, United States
Full record on ClinicalTrials.gov
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