Physical Activity to Reduce Joint Pain During Aromatase Inhibitor Therapy

Completed · Not applicable

Conditions studied: Joint Pain, Breast Cancer

In brief

For post-menopausal women diagnosed with hormone-receptor positive breast cancer tumors, aromatase inhibitors (AIs) are the standard adjuvant hormone treatment to prolong disease-free survival and time-to-recurrence. Unfortunately, joint pain/stiffness/achiness (arthralgia) is a common side-effect of AIs. This "proof-of-concept" study explores how an evidence-based physical activity (PA) program- the Arthritis Foundation's Walk with Ease (WWE) program- can be adapted for breast cancer survivors on AI therapy to: 1) Help them maintain or achieve recommended levels of PA, 2) reduce their joint pain/stiffness/achiness, and 3) thereby enable them to remain on AI therapy as prescribed.

Key facts

Study ID

NCT01900418

Run by

University of North Carolina, Chapel Hill

People needed

78

Starts

2013-08-01

Expected to finish

2016-06-01

Last updated by the study team

2016-08-08

Who can join

Age: 21 and older, up to 99. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Taking an aromatase inhibitor as adjuvant treatment for State I, II, or II breast cancer for at least 4 weeks
• Experiencing more than mild joint pain/symptoms
• 21 or older
• have permission from physician to engage in moderate intensity physical activity

You may not qualify if…

• Undergoing chemotherapy and/or radiation therapy at any time during the study period
• Scheduled for major surgery during the study period
• Presently engaged in high levels of physical activity on a daily basis
• Less than 21 years of age
• Unable to walk or engage in moderate intensity physical activity

Where it is running

• University of North Carolina — Chapel Hill, North Carolina, United States

Full record on ClinicalTrials.gov

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