A Safety and Efficacy Trial of Multiple Dosing Regimens of ABT-719 for the Prevention of Acute Kidney Injury in Subjects Undergoing High Risk Surgery

Stopped early · Phase 2 · Has a placebo group

Conditions studied: Cardiothoracic Surgery, Vascular Surgery

In brief

This study will evaluate the safety and efficacy of ABT-719 in patients undergoing high risk major surgery.

Key facts

Study ID

NCT01897519

Run by

AbbVie

People needed

56

Starts

2013-05-01

Expected to finish

2014-05-01

Last updated by the study team

2014-06-06

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients undergoing high risk major surgery in subjects with cardiovascular disease who are at risk of AKI.

You may not qualify if…

• Ongoing or recent history of sepsis
• Has recent documented acute kidney injury.
• Subject is scheduled to have a total or partial nephrectomy.

Where it is running

• Site Reference ID/Investigator# 96295 — Gainesville, Florida, United States
• Site Reference ID/Investigator# 96778 — Jacksonville, Florida, United States
• Site Reference ID/Investigator# 96301 — Tampa, Florida, United States
• Site Reference ID/Investigator# 96302 — Fort Wayne, Indiana, United States
• Site Reference ID/Investigator# 101961 — Indianapolis, Indiana, United States
• Site Reference ID/Investigator# 103356 — Boston, Massachusetts, United States
• Site Reference ID/Investigator# 96303 — Boston, Massachusetts, United States
• Site Reference ID/Investigator# 96997 — Grand Blanc, Michigan, United States
• Site Reference ID/Investigator# 97878 — Petoskey, Michigan, United States
• Site Reference ID/Investigator# 99377 — Royal Oak, Michigan, United States
• Site Reference ID/Investigator# 99317 — West Orange, New Jersey, United States
• Site Reference ID/Investigator# 96996 — New York, New York, United States
• Site Reference ID/Investigator# 96296 — Durham, North Carolina, United States
• Site Reference ID/Investigator# 102020 — Cleveland, Ohio, United States
• Site Reference ID/Investigator# 103355 — Columbus, Ohio, United States
• Site Reference ID/Investigator# 97556 — Pittsburgh, Pennsylvania, United States
• Site Reference ID/Investigator# 103316 — Providence, Rhode Island, United States
• Site Reference ID/Investigator# 102019 — Memphis, Tennessee, United States
• Site Reference ID/Investigator# 108255 — Charlottesville, Virginia, United States
• Site Reference ID/Investigator# 96300 — Milwaukee, Wisconsin, United States
• Site Reference ID/Investigator# 105755 — Aarhus N, Denmark
• Site Reference ID/Investigator# 105757 — Kolding, Denmark
• Site Reference ID/Investigator# 105756 — Odense C, Denmark

Full record on ClinicalTrials.gov

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