Increasing the Removal of Protein-Bound Solutes During Extended Hours Hemodialysis

Status unconfirmed · Not applicable

Conditions studied: End Stage Renal Failure on Dialysis

In brief

Hemodialysis keeps patients with renal failure alive but does not restore normal health. Retention of chemicals that bind to plasma proteins and are therefore poorly removed by dialysis may contribute to ill health in patients receiving conventional treatment. This proposal will test the effect of a new method designed to improve the removal of protein-bound solutes during dialysis. The effects on blood chemical levels of two different dialysis prescriptions will be tested in patients already undergoing nocturnal in-center hemodialysis three times weekly.

Key facts

Study ID

NCT01892839

Run by

Palo Alto Veterans Institute for Research

People needed

24

Starts

2013-07-01

Expected to finish

2016-12-01

Last updated by the study team

2015-07-13

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• stable on nocturnal in-center dialysis located close to Stanford University and VA Palo Alto

You may not qualify if…

• recent use of antibiotics
• gastrointestinal disease

Where it is running

• Satellite Redwood City — Redwood City, California, United States (enrolling)
• Stanford University — Stanford, California, United States (enrolling)

Full record on ClinicalTrials.gov

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