Clinical Characteristics of Dementias That Occur Remotely After Traumatic Brain Injury in Retired Military Personnel
Withdrawn before enrolling
Conditions studied: Dementia, Traumatic Brain Injury (TBI), Mild Cognitive Impairment (MCI), Chronic Traumatic Encephalopathy (CTE), Post-traumatic Stress Disorder (PTSD)
In brief
The objective of this study is to measure the frequency and clinical types of mild cognitive impairment (MCI) or dementia that occur among up to 150 military retirees with and without a history of traumatic brain injury (TBI) among residents of the Armed Forces Retirement Home, Washington D.C. and the Veterans Home of California-Yountville. Investigators will compare the characteristics of dementia in those who have had a prior TBI to the characteristics in those without a history of TBI. It is our hypothesis that the dementia or MCI among those with prior TBI has distinct neuropsychological features that distinguishes it from those with dementia or MCI without a history of TBI.
Key facts
- Study ID
- NCT01891383
- Run by
- Uniformed Services University of the Health Sciences
- People needed
- 0
- Starts
- 2013-07-01
- Expected to finish
- 2016-08-01
- Last updated by the study team
- 2019-01-18
Who can join
Age: 50 and older, up to 95. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Cases (with a history of TBI):
- Ages 50-95 years
- History of traumatic brain injury of sufficient severity to have resulted in medical attention (ascertained via the Ohio State University TBI Identification Questionnaire-OSU TBI-ID, and based on DoD/VA criteria)
- Residence in AFRH-Washington D.C. or the Veterans Home of California-Yountville
- MMSE score ≥ 20
- Capacity to provide consent to participate in research (assessment made by study physician)
- Ability to read and write English
- Controls (without a history of TBI):
- Ages 50-95 years
- No history of traumatic brain injury of sufficient severity to have resulted in medical attention (ascertained via the Ohio State University TBI Identification Questionnaire-OSU TBI-ID)
- Residence in AFRH-Washington or the Veterans Home of California-Yountville
- MMSE score ≥ 20
- Capacity to provide consent or assent to participate in research
- Ability to read and write English -
You may not qualify if…
- Cases (with a history of TBI):
- History of penetrating brain injury
- History of disabling neurological or psychiatric condition such as epilepsy (besides posttraumatic epilepsy), multiple sclerosis, cortical stroke, hypoxic-ischemic encephalopathy, encephalitis, or schizophrenia
- Controls (without a history of TBI):
- History of disabling neurological or psychiatric condition such as epilepsy, multiple sclerosis, cortical stroke, hypoxic-ischemic encephalopathy, encephalitis, or schizophrenia
Where it is running
- California Veterans Home-Yountville — Yountville, California, United States
- Armed Forces Retirement Home — Washington D.C., District of Columbia, United States
Full record on ClinicalTrials.gov
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