Body Temperature in Persons With Tetraplegia When Exposed to Heat
Completed
Conditions studied: Spinal Cord Injury
In brief
The deleterious effects of hyperthermia are well appreciated in able-bodied persons. However, the consequences of impaired regulation of normal body temperature on cognitive performance of persons with tetraplegia is not known. This study will provide the preliminary findings necessary for future work to design and explore physical and medical interventions to improve temperature regulation in those with tetraplegia with the goal of improved clinical care, health, and quality of life. The proposed study consists of 1 visit during which 20 subjects (10 with tetraplegia, 10 controls) will be exposed to 81°F for 40 minutes and then 95° F for up to 2 hours. Physiological as well as psychological processes will be monitored in all subjects during the study for safety and to determine differences in responses to exposure to hot ambient temperatures
Key facts
- Study ID
- NCT01890915
- Run by
- James J. Peters Veterans Affairs Medical Center
- People needed
- 21
- Starts
- 2013-05-01
- Expected to finish
- 2015-10-01
- Last updated by the study team
- 2016-03-03
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Between 18 and 65 years of age;
- Duration of injury ≥ 1 year;
- Level of SCI C4-T1;
- Euhydration (Subjects will be instructed to avoid caffeine and alcohol, maintain normal salt and water intake, and avoid strenuous exercise for 24 hours prior to study); and
- Age (± 5 years) and gender matched AB control group.
You may not qualify if…
- Known heart and/or blood vessel disease;
- High blood pressure;
- Kidney disease;
- Diabetes mellitus;
- Acute illness or infection;
- Dehydration;
- Pregnant women;
- Untreated thyroid disease, and
- Broken, inflamed, or otherwise fragile skin.
Where it is running
- Center of Excellence for the Medical Consequences of SCI, James J Peters VAMC — The Bronx, New York, United States
Full record on ClinicalTrials.gov
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