The Use of Alpha Lipoic Acid for the Treatment and Prevention of Diabetic Retinopathy

Stopped early · Not applicable

Conditions studied: Moderate Non-proliferative Diabetic Retinopathy

In brief

The purpose of this study is to evaluate the role of alpha lipoic acid in patients who have moderate non-proliferative diabetic retinopathy. The primary aim of this study is to test the hypothesis that the addition of alpha lipoic acid in a diabetic patient's therapeutic regimen can decrease the progression of diabetic retinopathy and preserve visual acuity.

Key facts

Study ID

NCT01880372

Run by

Ferris State University

People needed

1

Starts

2013-09-01

Expected to finish

2016-04-01

Last updated by the study team

2019-02-15

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Individual with diabetes mellitus type I or type II mild to moderate non-proliferative diabetic retinopathy which will be based on ETDRS grading scale
• Patient must be 18 years and older

You may not qualify if…

• Patients with severe non-proliferative or proliferative diabetic retinopathy
• Patients with macular edema
• Eye diseases that may interfere with visualization of the fundus such as preretinal hemorrhage, cataract, vitreous hemorrhage
• Patient that has undergone any type of interventional therapy for diabetic retinopathy (Such as laser photocoagulation, vitrectomy)
• Amblyopia
• Glaucoma
• Patient with cataract surgery within a period of 4 months
• Patients with other retinal diseases
• Patients on chronic administration of alpha lipoic acid
• Known intolerance/hypersensitivity to alpha lipoic acid
• Patient with history of dialysis in cases of renal insufficiency and history of kidney transplantation
• Malignancies or life threatening diseases as determined by the investigators
• Current history of drug or alcohol abuse
• Pregnant and breast feeding women
• Cognitively impaired patients
• Participation in a clinical trial within the last 30 days

Where it is running

• Ferris State University — Big Rapids, Michigan, United States
• Retina Specialists of Michigan — Grand Rapids, Michigan, United States

Full record on ClinicalTrials.gov

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