The Effects of Altering Physical Activity on Cardiometabolic Health

Completed · Not applicable

Conditions studied: Insulin Resistance

In brief

The effects of physical inactivity on variations in blood glucose and vascular health are not fully understood. The purpose of this study is to determine if an acute transition from physical activity to inactivity alters vascular health. Specifically, the investigators wish to examine in healthy, lean physically active individuals (obtaining greater than 10,000 steps/day) if decreasing physical activity (obtaining less than 5,000 steps/day) will alter blood flow following a meal a marker of vascular health. Furthermore, the investigators wish to examine if a one day return to physical activity (obtaining \>10,000 steps/day) can restore the detrimental effects on blood flow following a meal.

Key facts

Study ID

NCT01879059

Run by

University of Kansas Medical Center

People needed

13

Starts

2012-03-01

Expected to finish

2014-10-01

Last updated by the study team

2016-02-08

Who can join

Age: 19 and older, up to 35. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• BMI: less than 30 kg/m2
• Physically active: exercise greater than 60mins per week

You may not qualify if…

• smoking
• type 2 diabetes
• Underlying conditions that limit ability to exercise safely
• Recent weight gain or loss(> 5% of body weight in 3 months)
• Recent (< 3 mo) changes in medication use or dose
• Pregnancy

Where it is running

• University of Missouri — Columbia, Missouri, United States

Full record on ClinicalTrials.gov

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