Comparison of Reverse Remodeling and PVI Versus CFAE and/or Linear Lesions and PVI for Persistent AF

Withdrawn before enrolling · Phase 4

Conditions studied: Persistent Atrial Fibrillation

In brief

The hypothesis of this study is that by facilitating reverse atrial remodeling with maintenance of sinus rhythm in the weeks preceding ablation makes it feasible to perform a simple pulmonary vein isolation (PVI) with results equivalent or superior to more complex atrial ablation for patients with persistent AF.

Key facts

Study ID

NCT01877473

Run by

Valley Health System

People needed

0

Starts

2013-05-01

Expected to finish

2013-09-01

Last updated by the study team

2014-06-17

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Symptomatic persistent AF
• Failure of class I antiarrhythmic drug or amiodarone to control AF

You may not qualify if…

• Previous proarrhythmia to class III AAD including excessive QT prolongation or torsade-de-pointes
• Previous AF ablation procedure
• Congestive heart failure (NYHA III-IV functional class)
• Left ventricle ejection fraction less than 35%
• Left atrial diameter >55 mm
• Unwillingness to participate

Where it is running

• Valley Hospital — Ridgewood, New Jersey, United States

Full record on ClinicalTrials.gov

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