A Study Evaluating The PF-03084014 In Combination With Docetaxel In Patients With Advanced Breast Cancer

Stopped early · Phase 1

Conditions studied: Breast Cancer Metastatic

In brief

This study is aimed to determine the tolerability of the PF-03084014 plus docetaxel combination in patients with advanced breast cancer. Preliminary information about the efficacy of the combination will also be collected.

Key facts

Study ID

NCT01876251

Run by

Pfizer

People needed

30

Starts

2013-11-04

Expected to finish

2015-12-24

Last updated by the study team

2019-03-15

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of breast cancer with evidence of a) metastatic or b) locally recurrent/advanced disease.

You may not qualify if…

• Prior treatment with a gamma secretase inhibitors or other Notch signaling inhibitors.

Where it is running

• University of Alabama at Birmingham — Birmingham, Alabama, United States
• University of Alabama at Birmingham, IDS Pharmacy — Birmingham, Alabama, United States
• University of Alabama at Birmingham — Birmingham, Alabama, United States
• Stanford Cancer Institute — Stanford, California, United States
• Stanford Hospital & Clinics-DRUG SHIPMENT ADDRESS only — Stanford, California, United States
• Stanford Hospital & Clinics — Stanford, California, United States
• Stanford Women's Cancer Center — Stanford, California, United States
• Barbara Ann Karmanos Cancer Institute — Detroit, Michigan, United States
• Karmanos Cancer Institute (KCI) — Detroit, Michigan, United States
• UNC Cancer Hospital Infusion Pharmacy — Chapel Hill, North Carolina, United States
• UNC Hospitals, The University of North Carolina at Chapel Hill — Chapel Hill, North Carolina, United States
• Jules Bordet Institut — Brussels, Belgium
• Grand Hopital de Charleroi — Charleroi, Belgium
• Instituto Europeo di Oncologia — Milan, Italy
• Instituto Catalan de Oncologia de L'Hospitalet de Llobregat(ICO) — Barcelona, Spain
• Hospital Universitario 12 de Octubre — Madrid, Spain

Full record on ClinicalTrials.gov

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