AMBULATORY OXIMETRY MONITORING (AOM): a New Approach to Quantify Oxygen Desaturation in Ambulatory COPD Patients

Status unconfirmed

Conditions studied: Pulmonary Disease, Chronic Obstructive

In brief

Chronic obstructive lung disease (COPD) is characterized by airflow obstruction that is progressive over many years and is largely irreversible. Advanced COPD is associated with arterial oxygen desaturation leading to a series of complications and, ultimately, decreased survival. Long-term oxygen therapy can improve clinical outcomes in these patients, but the exact target of oxygen saturation that actually translates into improvements is not known. The basis for the work in this proposal is to focus a new approach to measure oxygen desaturation linked to daily activity. Accelerometers are used to measure daily activity and then synchronized with ambulatory oximetry to establish an activity/oxygen-saturation profile for individual patients. The three main objectives of this study are 1) determine the feasibility of AOM as a measurement of the temporal profile of oxygen saturation in patients with chronic lung disease; 2) determine if serial AOM-derived data is reliable and reproducible; and 3) determine thresholds of oxygen desaturation that are associated with different activity profiles

Key facts

Study ID

NCT01873092

Run by

VA New York Harbor Healthcare System

People needed

100

Starts

2003-05-01

Expected to finish

2016-12-01

Last updated by the study team

2013-06-07

Who can join

Age: 45 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Veteran patients with a diagnosis of COPD or other chronic lung disease
• able to read and understand English
• > 45 years old
• ambulatory and able to perform functional testing

You may not qualify if…

• unable or unwilling to give informed consent
• daily use of a motorized cart
• impairment of cognition or communication
• history of drug or alcohol treatment within the past 6 months
• poor peripheral blood flow to the finger rendering oxygen saturation by pulse oximetry unreliable
• Recent acute medical events (chest pain, discomfort, etc) that would suggest a contraindication to participate at the scheduled time

Where it is running

• VA, New York Harbor Healthcare Service — Brooklyn, New York, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.