DTI of the Brain and Cervical Spine: Evaluation in Normal Subjects and Patients With Cervical Spondylotic Myelopathy
Completed
Conditions studied: Cervical Spondylosis With Myelopathy
In brief
More than half of the middle-aged population has radiologic evidence of cervical spondylosis (Irvine 1965) and a subset of this population develops cervical spondylotic myelopathy (CSM), a condition in which the spinal cord is impaired, either by direct mechanical compression or indirectly by arterial deprivation and/or venous stasis. In this study we aim to test the hypothesis that diffusion tensor imaging can provide prognostic information on the integrity of the spine in these patients which is unavailable from conventional MRI images
Key facts
- Study ID
- NCT01868958
- Run by
- Emory University
- People needed
- 26
- Starts
- 2013-01-01
- Expected to finish
- 2015-06-01
- Last updated by the study team
- 2015-07-15
Who can join
Age: 30 and older, up to 70. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- 20 patients will be selected by an experienced team of orthopedic specialist from the Emory Orthopaedics \& Spine Center and will include patients suffering signs and symptoms of cervical myelopathy and with evidence of radiographic cervical cord compression with or without abnormal spinal cord signal intensity secondary to spondylosis.
- 20 controls : Aged matched to the patient group. No history of CSM.
You may not qualify if…
- Any history of significant trauma implicating the brain or cervical spine, including prior motor vehicle collision and history of prior brain, neck or cervical spine surgery.
- Any history of neurological disease
- Dental braces or similar orthodontic devices.
- Claustrophobia
Where it is running
- Center for Systems Imaging (CSI), Emory University — Atlanta, Georgia, United States
Full record on ClinicalTrials.gov
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