Pilot Study of Strength Testing in Overweight Women With or Without Insulin Resistance
Completed
Conditions studied: Obesity
In brief
Background: \- Some people who are obese may have decreased muscle strength. They may have greater muscle mass shown in scans, but they show poor results in exercise tests. Poor muscle strength might cause some of the difficulty with exercise performance. Researchers want to test muscle strength in the arms and legs of overweight women. They will also see how insulin resistance affects muscle strength in these women. Objectives: * To test muscle strength in overweight women. * To see if insulin resistance affects muscle strength. Eligibility: \- Women at least 18 years of age who are overweight (body mass index greater than 25 kg/m2). Design: * Participants will be asked to fast before having an initial blood test to measure glucose and insulin levels. * On a different day, they will have the strength testing. The first test will measure leg muscle strength by testing the quadriceps and the hamstrings. The second test will measure arm muscle strength by testing the biceps and triceps. The final test will measure hand muscle (grip) strength. * All the tests should take about an hour.
Key facts
- Study ID
- NCT01862757
- Run by
- National Heart, Lung, and Blood Institute (NHLBI)
- People needed
- 13
- Starts
- 2013-05-06
- Expected to finish
- 2015-03-13
- Last updated by the study team
- 2017-07-02
Who can join
Age: 18 and older, up to 70. Sex: female. Healthy volunteers: not accepted.
You may not qualify if…
- Medical or surgical condition that would prohibit upper and lower extremity strength testing (e.g., painful arthritis, prior knee or elbow surgery)
- Infection or injury to hand, knee or elbow requiring medical attention within 3 months of testing
Where it is running
- National Institutes of Health Clinical Center, 9000 Rockville Pike — Bethesda, Maryland, United States
Full record on ClinicalTrials.gov
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